Can diphenhydramine cause a miscarriage
One study found that antihistamines in early pregnancy, including diphenhydramine, did not increase the risk of miscarriage.Also, according to one study involving over 5,000 women, pregnant women who took antidepressants (ssris particularly) had a higher risk for miscarriage.Using promethazine late in pregnancy might increase the chance of slowed breathing (respiratory depression) in newborns.It is possible to suffer a miscarriage during any pregnancy.Human use of acetaminophen (paracetamol) during pregnancy has not shown a clear association with birth defects, miscarriage, or adverse maternal or fetal outcomes;
Benadryl also has the added benefit of easing nausea.